RNAseq Pipeline Description
RNA Sequencing Pipeline Overview
- Handles paired-end Illumina RNA sequencing data
- Supports both bacterial and eukaryotic genomes
- Automatic detection of organism type for parameter optimization
- Uses Bowtie2 for bacterial genomes with optimized parameters
- Supports local alignment with dovetail detection
- Generates sorted and indexed BAM files
- Handles unaligned reads separately for quality control
- Uses featureCounts for gene expression quantification
- Separate counting of rRNA reads
- Supports strand-specific protocols
- Minimum overlap length of 30bp for read assignment
- MultiQC report generation for quality metrics
- Alignment statistics and mapping quality assessment
- Results delivered via email upon completion
- Automated cleanup of intermediate files